Atorvastatin calcium
Atorvastatin calcium. Ciprofloxacin: Moderate Closely monitor for signs and symptoms of myopathy and rhabdomyolysis and consider atorvastatin dosage adjustment in patients also taking ciprofloxacin. Coadministration of ciprofloxacin, a moderate CYP3A4 inhibitor, with atorvastatin, a CYP3A4 substrate, may increase atorvastatin exposure resulting in atorvastatin-related toxicity; the risk may be increased with higher statin doses. Cobicistat: Major When administering atorvastatin concurrently with cobicistat, use the lowest starting dose of atorvastatin and carefully titrate while monitoring for adverse events myopathy ; DO NOT exceed a maximum daily atorvastatin dose of 20 mg daily.
Colchicine: Major Use caution and the lowest HMG-CoA reductase inhibitor dose necessary if coadministration with colchicine is necessary due to an increased risk of myopathy and rhabdomyolysis. There is no assurance that period monitoring of creatinine phosphokinase CPK will prevent the occurrence of myopathy. Case reports exist describing the development of myotoxicity with the concurrent administration of colchicine and HMG-CoA reductase inhibitors e.
Obat atorvastatin calcium trihydrate 20 mg
Setiap kaplet Litorcom mengandung Atorvastatin Calcium Trihydrate, dimana Atorvastatin merupakan obat golongan statin yang bekerja dengan cara menghambat kerja enzim yang berperan dalam pembentukan kolesterol sehingga kadar kolesterol dalam darah akan menurun. Dosis awal yang biasa: 10 atau 20 mg sekali sehari. Dosis dapat di sesuaikan dengan respons setelah pemberian selama 2-4 minggu.
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Gallery of Atorvastatin calcium
